Fish Peptides and Blood Pressure

High blood pressure Lower blood pressure naturally with fish peptides.

High blood pressure directly kills more than 50,000 people in the United States each year and contributes to more than 200,000 other deaths. This is a HUGE problem. To add insult to injury, the various medications used to treat high blood pressure often make patients feel worse due to side effects. Fortunately, there is a fantastic new-natural approach that is safe and effective to help lower blood pressure.

What are fish peptides?

Fish peptides are made up of a purified mixture of 9 small peptides (protein) derived from bonito (a member of the tuna family). These natural supplements are available in health food stores under Peptic ™ Fish Peptides. Peptic ™ does not contain heavy-metals (e.g., lead, mercury, etc.), pesticides, and other-contaminants.

How does it work to-lower blood pressure?

Fish peptides lower blood pressure by inhibiting ACE (angiotensin-converting enzyme). This enzyme converts angiotensin I into angiotensin II, a compound that increases fluid volume and the degree of constriction of the blood vessels. If we use the example of a garden hose to illustrate the pressure in your arteries, the formation of angiotensin II would be similar to pinching the hose while running the tap on full power. By inhibiting the construction of this compound, fish-peptides relax arterial walls, reduce fluid volume, and exert the highest known ACE inhibition of any naturally occurring substance available. 1.2

How are fish peptides different from drugs?

Medications that inhibit ACE are emerging as the drugs of choice for treating high blood pressure. The reason is-that, unlike other drug treatments (e.g., diuretics and beta-blockers), ACE inhibitors improve heart function and increase the flow of blood and oxygen to the heart, liver, and kidneys. This effect may explain why ACE inhibitors are the only antihypertensive drugs that seem to reduce the risk of having a heart attack. But unfortunately, they have no effect in reducing the risk of stroke.

The downside of ACE inhibitors is that their side effects include the development of a dry night cough, dizziness, lightheadedness, and headache. ACE inhibitors can also cause potassium build-up and-kidney problems, so potassium levels and kidney function should be checked. And all ACE inhibitors appear to be capable of producing a severe allergic reaction that could be dangerous to health.

Fish peptides do not appear-to produce any side effects based on human safety studies. The typical daily dose is 1.5 grams (or three tablets each day of Peptic ™ fish peptides), but even with a daily dose of 30 grams per day, not a single subject experienced any side effects, including a dry night cough. So familiar with ACE inhibitor medications.

Why are fish peptides no side effects?

The most likely reason is that its mechanism of action in inhibiting ACE is different than that of drugs. Research supports this theory. Medications indiscriminately block ACE by interfering with its move, whereas fish peptides interact differently. For example, ACE converts angiotensin I to angiotensin II by cleaving a small peptide. Medications work by directly blocking this action. Fish peptides work differently.

ACE reacts with fish peptides instead of angiotensin. In addition to competing with angiotensin through this effect, fish peptides are transformed into even more potent ACE inhibitors. Technically speaking, fish peptides are considered a “prodrug.” This term is used to describe substances transformed into more active components within the body. Although fish peptides have shown a good inhibition of ACE, the transformed ones exert an 800% greater activity.

Do fish peptides lower-blood pressure in people with normal blood pressure?

No, because due to the fantastic unique mechanism of action, fish peptides do not lower blood pressure in people with normal blood pressure, even when administered at levels 20 times higher than the dose level that lowers blood pressure in people with high tension. Medications do not work this way, and as a result, they often cause side effects when taken at higher doses.

Are there other naturally-occurring peptides that inhibit ACE?

Yes, other peptides have been shown to inhibit ACE, including peptides from milk, chicken, and other fish. However, what makes a-supplement like Peptic ™ Fish Peptides unique and superior is that although the others show activity in test tube studies when administered to animals (or humans), they are not active. The difference appears to-be the fact that fish peptides are absorbed intact-when taken orally, while the others are broken-down by digestive enzymes.

What kind of clinical effect-has been seen with PeptACE ™?

Three clinical studies have-shown that the fish peptide product Peptic ™ exerts significant blood pressure lowering effects in people with high-blood pressure (hypertension).2-4 The material appears to-be effective in approximately two-thirds of people with high blood pressure. The degree of blood pressure reduction in-these studies was quite-significant, typically reducing systolic by at least 10 mm Hg and diastolic by 7 mm Hg in people with borderline to mild hypertension. More significant reductions can be seen in people with higher initial readings in their blood pressure.

What is the correct dosage?

The typical dose is three 500 mg tablets each day. No side effects were indicated in clinical studies, and a risk study found no side effects with doses up to 30g daily. In addition, Peptic ™ does not affect blood-pressure in people without hypertension.

What else could a person do to help lower blood pressure?

As in other degenerative diseases, including arteriosclerosis, the development of high blood pressure is closely related to lifestyle and dietary factors. Some of the critical lifestyle factors that can cause high blood pressure are stress, lack of exercise, and smoking. Some of-the dietary factors include obesity, high sodium to potassium ratio, a diet high in sugar and low in fiber, an intake high in saturated fat and low in omega-3 fatty acids, and a diet low in calciummagnesium, and vitamin C.

Special foods for people with high blood pressure include celery, garlic, and onions, nuts and seeds or their oils for their essential fatty acid content, cold-water fish (salmon, mackerel, etc.), or fish oil products concentrated with EPA and DHA, green leafy vegetables for being a great source of calcium and magnesium, whole grains & legumes for their fiber and foods rich in vitamin C such as broccoli and citrus fruits. 

The celery seed extract is often an essential companion to a product like Peptic ™. This is because it contains 3-n-butylphthalide (3nB), which can also lower blood pressure. In animals, a small amount of 3nB lowered blood pressure by 12-14% .5 3nB appears to help reduce blood pressure by acting as both a diuretic and a vasodilator similar to drugs known as calcium channel blockers. Celery seed extract dosage is based on the 3nB level. For the standardized extract containing 85% 3nB, the dose is 150 mg each day.

Garlic and onions are-also important foods for lowering blood pressure. Additionally, taking a garlic supplement that provides at least 4000 mcg of allicin daily can also be beneficial. 6 Anyone with high blood pressure should take a high-potency multivitamin and mineral formula to ensure optimal levels of essential nutrients, especially magnesium.

Can I take Peptic ™ if I take medication to lower my blood pressure?

Yes. There are no known harmful effects with Peptic ™, including adverse drug reactions. In addition, Peptic ™ will not lower blood pressure below the-normal range even in people taking blood pressure-lowering medications.

Should I stop taking my blood pressure-lowering medications and switch to PeptACE ™?

No. Do not stop taking any medications unless advised by your doctor. Peptic ™ can be used together with your medicine. If applicable, after two weeks of use, your doctor may reduce the dose of your medications based on stabilization of blood pressure in the normal range.